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Kelly Services Sr. Scientist, Antibody Engineering in South San Francisco, California

Senior Scientist, Antibody Engineering

Kelly Science is seeking a technically savvy, highly motivated scientist with excellent attention to detail to join a leading research organization to expand antibody discovery capabilities for the South San Francisco site using the Berkeley Lights Beacon B cell cloning platform. The successful candidate must possess a combination of strong technical, communication and interpersonal skills to work effectively with a geographically diverse team across a broad range of biological targets and therapeutic areas.


  • Lead functional cell based assay development, optimization and troubleshooting activities to support selection of single B cells secreting antibodies with desired functional properties.

  • Become a subject matter expert and super-user on the Beacon platform, expanding capabilities, troubleshooting issues and executing workflows.

  • Interface with clients to strategize on screening strategies, assess the technical feasibility of new functional assays on Beacon and become an expert in upstream and/or downstream workflows to support antibody discovery through single B cell cloning.

  • Design and mentor scientists to execute antibody discovery campaigns using phage display and other antibody engineering and optimization projects.

  • Lead cross functional drug discovery teams, including coordinating meetings, presenting technical updates to clients and documenting discussions and action items in minutes.

  • Develop new target specific functional assays to expand capabilities on the Beacon platform including cytokine release, proliferation and cytotoxicity assays.

  • Manage and mentor junior level scientists in executing the B cell cloning workflow on and off the Beacon, assay development and troubleshooting efforts.

  • Support Business Development efforts by presenting technical capabilities to new clients.


  • Ph.D. with 5+ years R&D experience in a biotech/pharmaceutical environment or MS/BS with 12+ years experience in a biotech/pharmaceutical environment with expertise in molecular biology, biological sciences or related field.

  • Extensive hands-on experience with antibody engineering, humanization and various display technologies to support antibody discovery and development as evidenced by a strong publication record, patents and pipeline contributions

  • Highly motivated scientist with demonstrated ability to develop, troubleshoot and execute cell based functional assays, including immune cell assays.

  • Experience isolating and culturing primary cells, including B cells and PBMCs is a plus.

  • Ability to multi-task, with strong attention to detail, and precisely execute a diverse set of activities in a changing environment, often under time pressure.

  • With a mature, self-confident and well-balanced personality, it is essential that the candidate also possess a high standard of ethical and intellectual integrity.

Why Kelly ® ?

Kelly® Science & Clinical is your connection to premier scientific and clinical companies looking to hire talented people just like you. Every day, we match science professionals with dream jobs that fit their skills and interests—it’s the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background/education in science, so we know a thing or two about the science market and how to get you noticed.

About Kelly ®

At Kelly, we’re always thinking about what’s next and advising job seekers on new ways of working to reach their full potential. In fact, we’re a leading advocate for temporary/non-traditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live. Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world.

Kelly is an equal opportunity employer committed to employing a diverse workforce and providing accommodations for people with disabilities in all parts of the hiring process as required under its Employment Accommodation Policy. Kelly will work with applicants to meet accommodation needs that are made known to Kelly in advance.